N-Acetylneuraminic acid methyl ester

CAS No.: 50998-13-5   Request for quotation

Application:

Synthesis and pharmaceutical intermediate for use in the synthesis of glycolipids, glycopeptides and sialyl oligosaccharides. N-Acetylneuraminic acid methyl ester is also a very important intermediate for the synthesis of zanamivir and other active derivatives of sialic acid.

N-Acetylneuraminic acid methyl ester Specification

Appearance White to off-white powder   Standard Packing 10g/bag or per customer request
Assay (HPLC) ≥ 95%   Inventory Normally we have N-Acetylneuraminic acid methyl ester in stock
optical activity [α]20D -25.0 to -30.0 ° (C=1, H2O)    
Melting point 193.5-194.5°C (lit.)   N-Acetylneuraminic acid methyl ester physical parameters
Loss on drying ≤ 5%   CAS No: 50998-13-5
      Formula C12H21NO9
      Molecular Weight 323.30
      Synonym Methyl 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulopyranosonate; D-glycero-beta-D-galacto-2-Nonulopyranosonic acid; Methyl N-acetylneuraminate
      Structure N-Acetylneuraminic acid methyl ester
     
     
     
     
         
Certificate of Analysis N-Acetylneuraminic acid methyl ester COA      
Literature N-Acetylneuraminic acid methyl ester literature      
MSDS N-Acetylneuraminic acid methyl ester MSDS      
         
References:  
1. Pradeep Chopra, Robin J. Thomson, I. Darren Grice,Mark von Itzstein, et.al: Tetrahedron Letters. Volume 53, Issue 46, 14 November 2012, Pages 6254–6256. Rapid and clean microwave-assisted synthesis of N-acetylneuraminic acid methyl ester and its β-methyl glycoside
2. Alberto Marra,Pierre Sinay, et.al: Carbohydrate Research, Volume 190, Issue 2, 15 July 1989, Pages 317–322. Acetylation of N-acetylneuraminic acid and its methyl ester
 

Copyright © 2014. All Rights Reserved.
Home >>
N-Acetylneuraminic acid methyl ester