Ascomycin
Ascomycin Specification
Appearance | Amorphous white powder | Standard Packing | 10g/bag or per customer request | |
Purity (HPLC) | 95% | Inventory | Normally we have Ascomycin in stock | |
Total purity | < 5% | |||
Melting point | 156 - 161 °C | Ascomycin physical parameters | ||
Heavy metal | < 0.002% | CAS No: | 104987-12-4 | |
Water | < 3.0% | Formula | C43H69NO12 | |
Total Isomer of Ascomycin | < 5% | Molecular Weight | 792.01 | |
Synonym | FK520, FR 900520 | |||
Solubility | Soluble to 50 mM in DMSO and to 50 mM in ethanol | |||
Structure | ![]() |
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Certificate of Analysis | Ascomycin COA | |||
Literature | Ascomycin literature | |||
MSDS | Ascomycin MSDS | |||
References: | ||||
1. | Hatanaka et al (1988) FR-900520 and FR-900523, novel immunosuppressants isolated from a Streptomyces. II. Fermentation, isolation and physicochemical and biological characteristics. J.Antibiot (Tokyo). 41 1593. | |||
2. | Motamedi et al (1996) Characterization of methyltransferase and hydroxylase genes involved in the biosynthesis of the immunosuppressants FK506 and FK520. J.Bacteriol. 178 5243. PMID: 8752344. | |||
3. | Arndt et al (1999) Secretion of FK506/FK520 and rapamycin by Streptomyces inhibits the growth of competing Saccharomyces cerevisiae and Cryptococcus neoformans. Microbiology 145 1989. PMID: 10463165. | |||
4. | Revill et al (2002) Genetically engineered analogs of ascomycin for nerve regeneration. J.Pharmacol.Exp.Ther. 302 1278. PMID: 12183690. | |||
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