Naringenin

CAS No.: 67604-48-2   Request for quotation

Naringenin is a flavanone, a type of flavonoid, that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, and immune system modulator. It is the predominant flavanone in grapefruit. Naringenin has various effects such as anti-atherogenic, anti-oxidant, and anti-inflammatory effects.

Naringenin is effective at concentrations that are an order of magnitude below the toxic threshold in primary human hepatocytes and in mice. [3]

Naringenin belongs to the class of flavonoids called the flavanones. Naringenin is almost insoluble in water and is soluble in organic solvents such as alcohol.Naringenin is derived from the hydrolysis of glycone forms of this flavanone, such as naringin or narirutin.

Naringenin Specification

Appearance Light-Yellow Powder   Standard Packing 500g/bag or per customer request
Loss on drying ≤ 5%   Inventory Normally we have Naringenin in stock
Residue on ignition ≤ 5 %    
Heavy metals ≤ 10 ppm   Naringenin physical parameters
Residual Solvent ≤ 0.05%   CAS No: 67604-48-2
Pb ≤ 2 ppm   Formula C15H12O5
Assay ≥ 98%   Molecular Weight 272.25
Total of bacteria ≤ 1000 cfu/g   Synonym ()-Naringenin, ()-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4',5,7-Trihydroxyflavanone; 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Fungi ≤ 100 cfu/g   Structure Naringenine
E.coli Negative  
Salmosella Negative  
     
     
         
Certificate of Analysis Naringenin COA      
Literature Naringenin literature      
MSDS Naringenin MSDS      
         
References:  
1. Abdolkarim Mahrooz et. a.: Clinical Biochemistry 44(13), Supplement, September 2011, Pages S249. Naringenin is an inhibitor of human serum paraoxonase. DOI: 10.1016/j.clinbiochem.2011.08.617
2. Naringenin suppresses the production of thymic stromal lymphopoietin through the blockade of RIP2 and caspase-1 signal cascade in mast cells. DOI: 10.1016/j.ejphar.2011.09.163
3 Naringenin has also been shown to reduce hepatitis C virus production by infected hepatocytes (liver cells) in cell culture. This seems to be secondary to Naringenin's ability to inhibit the secretion of very-low-density lipoprotein by the cells.
 
 

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Naringenin