Naringin

CAS No.: 10236-47-2   Request for quotation

Naringin, a flavanone glycoside antioxidant, was reported to have antidiabetic and anti-apoptotic properties. Experiment result shows that angiogenesis was improved via naringin-mediated inhibition of hyperglycemia, oxidative stress, down-regulation of inflammatory mediator expression and up-regulation of growth factor expression, leading to improved wound healing of DFU.

Naringin improved wound area, glycated Hb, serum glucose level and insulin.
Naringin up-regulated IFG-1, TGF-β, VEGF-c, Ang-1 and collagen-1 mRNA expression.
TNF-α, IL-1β and IL-6 mRNA expression were down-regulated by naringin.
Naringin induced angiogenesis via inflammatory mediator & growth factor modulation.

Naringin Specification

Appearance Off-White powder   Standard Packing 500g/bag or per customer request
Loss on drying ≤ 5%   Inventory Normally we have Naringin in stock
Residue on ignition ≤ 5 %    
Heavy metals ≤ 10 ppm   Naringin physical parameters
Residual Solvent ≤ 0.05%   CAS No: 10236-47-2
As ≤ 5 ppm   Formula C27H33O14
Assay ≥ 98%   Molecular Weight 580.53
Total plate count ≤ 1000 cfu/g   Synonym 4',5,7-Trihydroxyflavanone 7-rhamnoglucoside, Naringenine-7-rhamnosidoglucoside
Yeast & Mold ≤ 100 cfu/g   Structure Naringin
E.coli Negative  
Salmosella Negative  
     
     
         
Certificate of Analysis Naringin COA      
Literature Naringin literature      
MSDS Naringin MSDS      
         
References:  
1. Naringin, a flavanone glycoside, promotes angiogenesis and inhibits endothelial apoptosis through modulation of inflammatory and growth factor expression in diabetic foot ulcer in rats. DOI: 10.1016/j.cbi.2014.05.012
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Naringin