Ergosterol

CAS No.: 57-87-4   Request for quotation
 

Ergosterol (ergosta-5,7,22-trien-3-ol) is a sterol found in fungi, and named for ergot, the common name of members of the fungal genus Claviceps from which ergosterol was first isolated. Ergosterol is a component of yeast and other fungal cell membranes, serving many of the same functions that cholesterol serves in animal cells.Its specificity in higher fungi is thought to be related to the climatic instabilities (highly varying humidity and moisture conditions) encountered by these organisms in their typical ecological niches (plant and animal surfaces, soil). Thus, despite the added energy requirements of ergosterol synthesis (if compared to cholesterol), ergosterol is thought to have evolved as a nearly ubiquitous, evolutionarily advantageous fungal alternative to cholesterol.

Ergosterol powder is an irritant to skin, eyes, and the respiratory tract. Ingestion of large amounts can cause hypercalcemia, which (if prolonged) can lead to calcium salt deposits in the soft tissues and, in particular, the kidneys.

Ergosterol Specification

Appearance White crystalline powder   Standard Packing 100g/bag or per customer request
Melting range 158° -164°   Inventory Normally we have Ergosterol in stock
Specific rotation > -120°    
Loss on drying <3%   Ergosterol physical parameters
Assay ≥98%   CAS No: 57-87-4
      Formula 396.65
      Molecular Weight C28H44O
      Synonym Ergosterol; Provitamin D2; (22E)-Ergosta-5,7,22-trien-3-Beta-ol
      Structure Ergosterol
   
       
       
       
   

Ergosterol Biosynthesis:

Ergosterol Biosynthesis

 
Certificate of Analysis Ergosterol COA      
Literature Ergosterol literature      
MSDS Ergosterol MSDS      
         
References:  
1. Kelly, S.L., Lamb, D.C., Corran, A.J., Baldwin, B.C., Parks, L.W. and Kelly, D.E. (1995) Purification and reconstitution of activity of Saccharomyces cerevisiae P450 61, a sterol 22-desaturase. FEBS Lett. 377, 217-220.
2. Yoshida, Y. and Aoyama, Y. (1991) Cytochromes P-450 in the ergosterol biosynthesis. In Ruckpaul, K. and Rein, H., Eds. Frontiers in Biotransformation, vol. 4: Microbial and Plant Cytochromes P-450: Biochemical Characteristics, Genetic Engineering and Practical Implications. Taylor & Francis, London, pp. 127-148.
 
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